Epic's vicepresident Mark Rein said in an interview with Videogamer that Unreal Engine 4 games can easily be ported to the WiiU if developers desire. The engine is "supremely scalable".
However, Rein also states that Epic has no intention of bringing its next generation game development engine to the WiiU, and suggested that Unreal Engine 3 was a better fit for Nintendo's hardware.
"I'll state that I don't think it's our intention to bring Unreal Engine 4 to Wii U" he said. "But Unreal Engine 4 is going to be supremely scalable. We'll run on mobile phones and on a wide variety of things, so if a customer decides they want to port an Unreal Engine 4 game to Wii U, they could. But Unreal Engine 3 is a really good fit for that platform."
To this Rein adds:
"We have Unreal Engine 3 running on Wii U, you saw games at the Nintendo press conference again this year - a fantastic demo by our friends at Warner Bros. showing Arkham City running on Wii U. And Aliens: Colonial Marines is coming on Wii U, that's also Unreal. There's, I'm sure, several others. Mass Effect was announced for it as well. So we're certainly playing a role there with Unreal Engine 3.
Recently, Fortnite was announced to be the first game running on Unreal Engine 4.